Translational research on Diabetic cardiomyopathy

vers des applications cliniques prochaines?

8:30 am



8:50 am   Introduction : Christian Boitard, Director ITMO Pathophysiology Metabolism Nutrition

Session 1: Pathophysiological basis of myocardial alteration

Chairs: Jérémy Fauconnier (Montpellier), Xavier Prieur (Nantes), Bart Staels (Lille)

9:00 am  

Role of EPAC1 in diabetic cardiomyopathy - Frank Lezoualc'h, Toulouse

9:15 am   Disruption of reticulum-mitochondria contact sites in metabolic diseases: from type 2 diabetes to diabetic cardiomyopathy - Jennifer Rieusset, Lyon
9:30 am   NAD metabolism and signaling in heart diseases - Mathias Mericskay, Chatenay Malabry
9:45 am   Myocardial metabolic remodeling and protective role of AMPK - Luc Bertrand, Bruxelles
10:00 am   Joint discussion
10:15 am   Coffee break

Session 2: Environment and diabetes

Chairs: Hélène Duez (Lille), Bénédicte Gaborit (Marseille), Nicolas Venteclef (Paris)

10:30 am   Impact of obesity and fat tissue - Maria Pini, Créteil
10:50 am   Impact of immunity and microbiota - Agnès Lehuen, Paris
11:10 am   Key note lecture: Metabolism and cell senescence - Elizabeth Blackburn, San Francisco
11:45 am  

 Joint discussion

12:00 pm   Lunch break - Posters visit

Session 3: Which clinical phenotyping ?

Chairs: Monique Bernard (Marseille), Geneviève Derumeaux (Créteil), Samy Hadjadj (Nantes)

2:00 pm   Cardiac imaging options to study DCM - Jan D'hooge, Leuven
2:15 pm   Microvascular dysfunction in diabetes related heart failure - Chim Lang, Dundee
2:30 pm   Ultrafast UltraSound Imaging - Mickael Tanter, Paris
2:45 pm   Metabolomics for clinical phenotyping - Christophe Junot, Saclay
3:00 pm   Joint discussion

3:15 pm

Moderated Poster Discussion

Discussants:  Fabrizio Andreelli (Paris), Marion Laudette (Toulouse)
                          David Montaigne (Lille), Laetitia Pereira (Châtenay Malabry)


Session 4: Diabetic cardiomyopathy evolutivity

Chairs: Philip Janiak (Chilly Mazarin), Michel Marre (Paris), Dominique Valla (Paris)

4:30 pm   Health trajectories: Sleep apnea as a user case - Jean-Louis Pépin, Grenoble

4:45 pm


Patterns of comorbidities in type 2 diabetes - Corneliu Henegar, Créteil

5:00 pm   Endothelial dysfunction in HFpEF - Thierry Couffinhal, Bordeaux
5:15 pm   Joint discussion
5:30 pm   Conclusion : Geneviève Derumeaux, Network coordinator

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